Publications

Recent publications:

2017

Panagopoulos A, Taraviras S, Lygerou Z (2017). Mismatch Repair regulates Cdt1 after UV damage. Cell Cycle. 2017 Apr 20:0. doi: 10.1080/15384101.2017.1319687.

Giakoumakis NN, Rapsomaniki MA, Lygerou Z (2017).Analysis of Protein Kinetics Using Fluorescence Recovery After Photobleaching(FRAP).Methods Mol Biol. 2017;1563:243-267. doi: 10.1007/978-1-4939-6810-7_16.

Kyrousi C,Lygerou Z, Taraviras S.(2017)How a radial glial cell decides to become a multiciliated ependymal cell. Glia.2017 Jul;65(7):1032-1042. doi: 10.1002/glia.23118.

Patmanidi AL, Champeris Tsaniras S, Karamitros D, Kyrousi C,Lygerou Z , Taraviras S. (2017) Concise Review: Geminin-A Tale of Two Tails: DNA Replication and Transcriptional/Epigenetic Regulation in Stem Cells. Stem Cells. 2017 Feb;35(2):299-310. doi: 10.1002/stem.2529.

2016

Kyrousi C, Lalioti ME, Skavatsou E, Lygerou Z, Taraviras S.(2016)Mcidas and GemC1/Lynkeas specify embryonic radial glial cells. Neurogenesis (Austin). 2016, 3(1):e1172747.

Patmanidi AL, Kanellakis NI, Karamitros D, Papadimitriou C, Lygerou Z, Taraviras S.(2016) Whole transcriptome data analysis of mouse embryonic hematopoietic stem and progenitor cells that lack Geminin expression. Data Brief. 2016 Mar 12;7:889-93.

K. Vakaloglou, G. Chrysanthis, M-A Rapsomaniki, Z. Lygerou, C. Zervas (2016) IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover. Cell Reports 2016, 17:2268-2282.

M. Arbi, D-E Pefani, C. Kyrousi, M-E Lalioti, A. D. Papanastasiou, S.Taraviras and Z. Lygerou.(2016) GemC1 controls multiciliogenesis in the airway epithelium” EMBO Reports 2016, Mar; 17(3):400-13.

Stathopoulou A, Natarajan D, Nikolopoulou P, Patmanidi AL, Lygerou Z, Pachnis V, Taraviras S.(2016) Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis. Developmental Biology 2016, Jan 15;409(2):392-405.

2015

Caillat C, Fisha A, Pefani E-D, Taraviras S , Lygerou Z and Perrakis A. (2015) The crystal structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins. Acta Crystallographica D. 2015, Nov 1;71(Pt 11):2278-86

Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Götz M, Lygerou Z, Taraviras S.(2015) Mcidas and GemC1/Lynkeas are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development 2015, 142(21):3661-74

Kourti M, Ikonomou G, Giakoumakis NN, Rapsomaniki MA, Landegren U, Siniossoglou S, Lygerou Z, Simos G, Mylonis I.(2015) CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation. Cell Signal. 2015 Jun;27(6):1129-40.

Rapsomaniki, M. A., Cinquemani, E., Giakoumakis, N. N., Kotsantis, P., Lygeros, J., & Lygerou Z. (2015). Inference of protein kinetics by stochastic modeling and simulation of fluorescence recovery after photobleaching experiments. Bioinformatics, 2015 Feb 1;31(3):355-62.

Karamitros D, Patmanidi AL, Kotantaki P, Potocnik AJ, Bähr-Ivacevic T, Benes V, Lygerou Z, Kioussis D, Taraviras S. (2015). Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors. Development, 2015 Jan 1;142(1):70-81.

2014

Champeris Tsaniras S, Kanellakis N, Symeonidou IE, Nikolopoulou P, Lygerou Z, Taraviras S. (2014) Licensing of DNA replication, cancer, pluripotency and differentiation: An interlinked world? Semin Cell Dev Biol. , 2014 Jun;30:174-80

2013

Symeonidou IE, Kotsantis P, Roukos V, Rapsomaniki MA, Grecco HE, Bastiaens P, Taraviras S, Lygerou Z. (2013) Multi-step loading of human Mini-Chromosome Maintenance Proteins in live human cells.  J Biol. Chem.  288(50): 35852-67

Caillat C, Pefani ED, Gillespie PJ, Taraviras S, Blow JJ, Lygerou Z, Perrakis A. (2013) The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing. J Biol. Chem.  288(44):31624-34

Dimaki M.,  Xouri G.,  Symeonidou I.E., Sirinian H., Nishitani H., Taraviras S. and Lygerou Z. (2013) Cell-cycle dependent subcellular translocation of human Geminin.  J Biol. Chem.  288(33):23953-63

Iliou M, Kotantaki P, Karamitros D, Spella M, Taraviras S and Lygerou Z. (2013) Reduced Geminin levels promote cellular senescence. Mech Ageing Dev. 134:10-23

2012

Symeonidou IE, Taraviras S, Lygerou Z. (2012) Control over DNA replication in time and space. FEBS Letters. 586(18):2803-12

Rapsomaniki MA, Kotsantis P, Symeonidou IE, Giakoumakis NN, Taraviras S and Lygerou Z (2012) easyFRAP: an interactive, easy-to-use tool for qualitative and quantitative analysis of Fluorescence Recovery After Photobleaching data. Bioinformatics. 28(13):1800-1

Stathopoulou A, Roukos V, Petropoulou C, Kotsantis P, Karantzelis N, Nishitani H, Lygerou Z, Taraviras S. (2012) Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs. PLoS ONE. 7(3):e34621

Zoi Lygerou, K. K. Koutroumpas and John Lygeros (2012) DNA Replication. Encyclopedia of Systems Biology, in press

2011

Karamitros D, Kotantaki P, Lygerou Z, Kioussis D, Taraviras S. (2011) T cell proliferation and homeostasis: an emerging role for the cell cycle inhibitor geminin. Crit Rev Immunol.,  31(3):209-31.

Spella M, Kyrousi C, Kritikou E, Stathopoulou A, Guillemot F, Koussis D, Pachnis, Lygerou Z, Taraviras S (2011) Geminin regulates cortical progenitor proliferation and differentiation. Stem Cells, 29:1269-1282

Pefani DE, Dimaki M, Spella M, Karantzelis N, Mitsiki E, Kyrousi C, Symeonidou IE, Perrakis A, Taraviras S, Lygerou Z. (2011) Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression. J. Biol. Chem. 286:23234-46

Roukos V, Kinkhabwala A, Colombelli J, Kotsantis P, Taraviras S, Nishitani H, Stelzer E, Bastiaens P, and Lygerou Z. (2011) Dynamic Recruitment of the Licensing Factor Cdt1 to Sites of DNA Damage J. Cell Science. 124:422-432

2010

Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S (2010) Life without geminin. Cell Cycle. 9(16):3181-5.

Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, Taraviras S. (2010) Differential Geminin Requirement for Proliferation of Thymocytes and Mature T Cells. J Immunol. 184(5):2432-41

2009

De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A. (2009) Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing. Proc Natl Acad Sci USA. 106(47):19807-12

2008

J. Lygeros, K. Koutroumpas, S. Dimopoulos, I. Legouras, P. Kouretas, C. Heichinger, P. Nurse, Z. Lygerou (2008) Stochastic hybrid modelling of DNA replication across a complete genome. Proc Natl Acad Sci USA. 105:12295-12300.

E.Cinquemani, V.Roukos, Z.Lygerou, J.Lygeros (2008) Numerical analysis of FRAP experiments for DNA replication and repair. Proceedings of the 47th IEEE Conference on Decision and Control. Cancun, Mexico, December 2008 (peer reviewed conference paper).

K. Koutroumpas, Z. Lygerou, J. Lygeros (2008) Parameter Identification for a DNA Replication Model. Proceedings of the IEEE International Conference on BioInformatics and BioEngineering, Athens, October 2008 (peer reviewed conference paper)

 

A complete list of publications by our lab on PubMed can be found here

The Google Scholar profile of Zoi Lygerou can be found here
 

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